AnyPS5 provides a toolchain for running PlayStation 5 games on personal computers by translating PS5 executables directly to the host operating system's native format. According to its documentation, the project includes a relinker that converts PS5 executable files to the target system's native executable format and supplies implementations of the PlayStation 5's system libraries (known as PRX libraries) as dynamically linked libraries, allowing the game to call these functions without any emulation layer or separate runtime process.

The project tracks its progress by measuring how many PS5 system library functions have been implemented, reporting approximately 87% of these functions mapped to date. The documentation clarifies that this percentage reflects only the functions currently declared in the project's core/libs/prx directory, not the total set of every possible PS5 system function, and that the number grows as more functions are declared.

Verified compatibility demonstrations include the 2D platformer 'Dreaming Sarah,' which runs at a stable 60 frames per second on a system equipped with a GTX 1050 Ti graphics card and an i5-7500 processor clocked at 3.4 GHz. AnyPS5 also incorporates a shader recompiler that converts PS5-specific shaders to the standardized SPIR-V format, with output validated via Spirv-Tools when the ANYPS5_ENABLE_SPIRV_TOOLS option is enabled; unsupported or unexpected states cause the program to terminate after printing a std::runtime_error message to stderr.